VAX: True Targets…
Submitted RT
Tucker Carlson: Uncovered Emails Show Fauci Supported ‘Grotesque’ Experiments at Wuhan Lab. https://
Video (section): 11 Mins 18 Secs.
Plus, from blog: The Virology Journal, screenshot, August 22 2005. ‘Chloroquine is a Potent Inhibitor of Sars Coronavirus and Spread.’ Martin J Vincent,et al. https://www.ncbi.nlm.nih.gov/
Background: Severe Acute Respiratory Syndrome (SARS) is caused by a newly discovered Coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
Results: We report, however, that Chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both Prophylactic and Therapeutic advantage. In addition to the well-known functions of Chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, Angiotensin-Converting Enzyme 2 (ACE-2). This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.
Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favourable inhibition of virus spread was observed when the cells were either treated with Chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
Chloroquine, a 9-aminoquinoline that was identified in 1934, is a weak Base that increases the pH of Acidic vesicles. When added extracellularly, the non-protonated portion of chloroquine enters the cell, where it becomes protonated and concentrated in acidic, low-pH Organelles, such as Endosomes, Golgi vesicles, and Lysosomes. Chloroquine can affect virus infection in many ways, and the antiviral effect depends in part on the extent to which the virus utilises Endosomes for entry. Chloroquine has been widely used to treat human diseases, such as Malaria, Amoebiasis, HIV, and Autoimmune diseases, without significant detrimental side effects … Since Chloroquine inhibited SARS-CoV infection when added before or after infection, we hypothesised that another common Lysosomotropic agent, NH4Cl, might also function in a similar manner. Ammonium Chloride has been widely used in studies addressing Endosome-mediated virus entry. Coincidently, NH4Cl was recently shown to reduce the transduction of Pseudotyped viruses decorated with SARS-CoV Spike Protein. In an attempt to examine if NH4Cl functions similarly to Chloroquine, we performed infection analyses in Vero E6 Cells before they were treated with various concentrations of NH4Cl. In both cases, we observed a 93–99% inhibition with NH4Cl at ≥ 5 mM. These data indicated that NH4Cl (≥ 5 mM) and Chloroquine (≥ 10 μM) are very effective in reducing SARS-CoV infection. These results suggest that effects of Chloroquine and NH4Cl in controlling SARS CoV infection and spread might be mediated by similar mechanism(s).
COMMENT: Covid Cures Coverup. It was Never about Covid, the Intent was always the Agenda for Mandated World-Wide ‘vaccines’ – Massive Profits for Big Pharma – While Depopulation was the True Target.