{"id":105625,"date":"2022-01-31T18:46:22","date_gmt":"2022-01-31T22:46:22","guid":{"rendered":"http:\/\/stateofthenation.co\/?p=105625"},"modified":"2022-01-31T18:46:22","modified_gmt":"2022-01-31T22:46:22","slug":"long-covid-risk-tied-to-composition-of-gut-microbiome","status":"publish","type":"post","link":"https:\/\/stateofthenation.co\/?p=105625","title":{"rendered":"\u2018Long COVID\u2019 risk tied to composition of gut microbiome"},"content":{"rendered":"<p><!--more-->by Amanda Christmas<\/p>\n<p>Could the severity and length of a COVID-19 infection hinge on the health of a patient\u2019s gut? A recent study suggests that \u201cprofiling\u201d the gut microbiome (the environment where bacteria, viruses, and fungi live in the intestines) will help to determine who might develop post-acute COVID-19 syndrome, or \u201clong Covid.\u201d<\/p>\n<p><strong>Lingering Symptoms and the Gut<\/strong><\/p>\n<p>A significant number of people who were infected with COVID-19 reported persistent complications and symptoms as long as six months after \u201crecovery.\u201d The most commonly noted issues were fatigue, muscle weakness, and insomnia.<\/p>\n<p>With about 75% of the immune system living in the gut, any disruption to the microbiome can lead to a difficult and long recovery, especially from a severe infection that attacks major organs. The researchers suggest that this may have a role in long COVID even though it\u2019s not completely clear what the cause is or why only some patients will develop it. More and more research is indicating that a damaged\u00a0<a href=\"https:\/\/www.gutnews.com\/gut-biome-arthritis-psoriasis-chronic-illness\/\" target=\"_blank\" rel=\"noreferrer noopener\">gut microbiome plays a major role<\/a>\u00a0in how severe COVID-19 infection is.<\/p>\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1631\" src=\"https:\/\/www.gutnews.com\/wp-content\/uploads\/2022\/01\/fusion-medical-animation-rnr8D3FNUNY-unsplash-1024x576.jpg\" sizes=\"auto, (max-width: 440px) 100vw, 440px\" srcset=\"https:\/\/www.gutnews.com\/wp-content\/uploads\/2022\/01\/fusion-medical-animation-rnr8D3FNUNY-unsplash-1024x576.jpg 1024w, https:\/\/www.gutnews.com\/wp-content\/uploads\/2022\/01\/fusion-medical-animation-rnr8D3FNUNY-unsplash-475x267.jpg 475w, https:\/\/www.gutnews.com\/wp-content\/uploads\/2022\/01\/fusion-medical-animation-rnr8D3FNUNY-unsplash-768x432.jpg 768w, https:\/\/www.gutnews.com\/wp-content\/uploads\/2022\/01\/fusion-medical-animation-rnr8D3FNUNY-unsplash-1536x864.jpg 1536w, https:\/\/www.gutnews.com\/wp-content\/uploads\/2022\/01\/fusion-medical-animation-rnr8D3FNUNY-unsplash-2048x1152.jpg 2048w, https:\/\/www.gutnews.com\/wp-content\/uploads\/2022\/01\/fusion-medical-animation-rnr8D3FNUNY-unsplash-300x169.jpg 300w\" alt=\"COVID-19 \/ SARS-CoV-2\" width=\"440\" height=\"247\" \/><figcaption>More and more research is indicating that a damaged\u00a0<a href=\"https:\/\/www.gutnews.com\/gut-biome-arthritis-psoriasis-chronic-illness\/\" target=\"_blank\" rel=\"noreferrer noopener\">gut microbiome plays a major role<\/a><br \/>\nin how severe COVID-19 infection is.\u00a0 (Photo by Fusion Medical Animation on Unsplash)<\/figcaption><\/figure>\n<\/div>\n<p><strong>The Study<\/strong><\/p>\n<p>Over a six month period, the researchers analyzed stool samples and the aerobic capacity and endurance of 106 patients with various levels of severity of COVID-19 to track any changes in their microbiomes. The team compared the findings with a group of 68 people who were not infected with the virus.<\/p>\n<p>After checks at three and six months, around 80% of the infected patients showed symptoms of long COVID. Further study of the data showed that those patients with long COVID had much more disruption in the gut. Those who did not have long COVID had similar microbiomes to those who had not had the COVID-19 infection.<\/p>\n<p>Some of the significant findings in this study were based on the\u00a0<a href=\"https:\/\/www.gutnews.com\/gut-bacteria-race-insulin-resistance\/\" target=\"_blank\" rel=\"noreferrer noopener\">specific bacterial levels<\/a>\u00a0found in the patients. As the study progressed, those with long COVID had significantly more \u201cunfriendly\u201d bacteria and more changes in the gut microbiome. Additionally, the \u201cgood\u201d bacteria known to boost immunity was completely gone from the long COVID patients at the six month check.<\/p>\n<p>Because this was an observational study, it doesn\u2019t establish cause. However, researchers say that their findings support previously proven theories that identify a disrupted gut microbiome as the cause of a variety of long-term health issues.<\/p>\n<p>\u201cIn summary, altered gut microbiome composition is strongly associated with persistent symptoms in patients with COVID-19 up to 6 months after clearance of SARS-CoV-2 virus.<\/p>\n<p>\u201cConsidering the millions of people infected during the ongoing pandemic, our findings are a strong impetus for consideration of microbiota modulation to facilitate timely recovery and reduce the burden of post-acute COVID-19 syndrome,\u201d conclude the researchers in a\u00a0<a href=\"https:\/\/www.eurekalert.org\/news-releases\/940894\" target=\"_blank\" rel=\"noreferrer noopener\">statement<\/a>.<\/p>\n<p>The study can be found in the journal\u00a0<em><a href=\"https:\/\/gut.bmj.com\/content\/early\/2022\/01\/05\/gutjnl-2021-325989\" target=\"_blank\" rel=\"noreferrer noopener\">Gut.<\/a><\/em><\/p>\n<p>___<\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"b0yCNW0Kpz\"><p><a href=\"https:\/\/gutnews.com\/long-covid-gut-microbiome\/\">&#8216;Long COVID&#8217; risk tied to composition of gut microbiome<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;&#8216;Long COVID&#8217; risk tied to composition of gut microbiome&#8221; &#8212; Gut Health News\" src=\"https:\/\/gutnews.com\/long-covid-gut-microbiome\/embed\/#?secret=a7X3ZoRc8e#?secret=b0yCNW0Kpz\" data-secret=\"b0yCNW0Kpz\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-105625","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/stateofthenation.co\/index.php?rest_route=\/wp\/v2\/posts\/105625","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stateofthenation.co\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stateofthenation.co\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stateofthenation.co\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stateofthenation.co\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=105625"}],"version-history":[{"count":0,"href":"https:\/\/stateofthenation.co\/index.php?rest_route=\/wp\/v2\/posts\/105625\/revisions"}],"wp:attachment":[{"href":"https:\/\/stateofthenation.co\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=105625"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stateofthenation.co\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=105625"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stateofthenation.co\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=105625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}