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By Jon Miltimore
\nRealClear Politics<\/p>\n
This past week Minnesota became the second state to reject regulations that effectively ban the controversial drug hydroxychloroquine for use by COVID-19 patients.<\/p>\n
The\u00a0decision<\/a>, which comes two weeks after the Ohio Board of Pharmacy\u00a0reversed\u00a0<\/a>an effective ban of its own, was rightfully praised by local health care advocates.\u00a0 \u201cWe are pleased that Governor [Tim] Walz lifted his March 27 Executive Order 20-23 restrictions on chloroquine and hydroxychloroquine,\u201d\u00a0said<\/a> Twila Brase, president of Citizens\u2019 Council for Health Freedom.<\/p>\n The reversal by Walz, a first-term Democrat, clears the way for doctors to prescribe hydroxychloroquine, a drug commonly used to treat malaria and other conditions but one the FDA has\u00a0declined\u00a0<\/a>to recommend for COVID-19 treatment.<\/p>\n The decision is the latest development in the weird saga of arguably the most divisive drug in modern history. The acrimony began in March after President Trump\u00a0tweeted\u00a0<\/a>that hydroxychloroquine had the potential to be \u201cone of the biggest game changers in the history of medicine\u201d as a treatment for the coronavirus.<\/p>\n The tweet and similar statements provoked an avalanche of media criticism, with many claiming that the president was going to get people killed. Critics pointed out that medical evidence suggests the medication is\u00a0linked to a fatal arrhythmia<\/a>\u00a0and some trials show\u00a0no benefits<\/a>\u00a0in coronavirus treatments.<\/p>\n Though his critics are likely loath to admit it, there\u2019s reason to believe the president may have been on to something. In recent weeks a chorus of voices in the medical community has emerged to challenge the view that hydroxychloroquine is ineffective as a COVID treatment. Dr. Harvey A. Risch, a professor of epidemiology at the Yale School of Public Health, said a full analysis of the literature suggests hydroxychloroquine may be the key to defeating the coronavirus.<\/p>\n \u201cPhysicians who have been using these medications in the face of widespread skepticism have been truly heroic,\u201d Risch\u00a0wrote\u00a0<\/a>in Newsweek, adding that a full review of the COVID literature on the drug shows \u201cclear-cut and significant benefits.\u201d<\/p>\n Prescribing hydroxychloroquine in the early stages of the virus is key, Risch said, and others agree. Steven Hatfill, a veteran virologist and adjunct assistant professor at the George Washington University Medical Center, says the literature supporting hydroxychloroquine is overwhelming.<\/p>\n \u201cThere are now 53 studies that show positive results of hydroxychloroquine in COVID infections,\u201d Hatfill\u00a0wrote\u00a0<\/a>in RealClearPolitics. \u201cThere are 14 global studies that show neutral or negative results — and 10 of them were of patients in very late stages of COVID-19, where no antiviral drug can be expected to have much effect.\u201d<\/p>\n One of the positive studies<\/a>, published by Henry Ford Health System, was a large-scale retrospective of six hospitals. Analyzing 2,541 patients, it found that those treated with hydroxychloroquine alone died at about half the rate of patients not treated with it.<\/p>\n It\u2019s unclear if it was this research that prompted Walz to reverse his March ruling, which ordered the Board of Pharmacists to instruct pharmacists to not issue hydroxychloroquine prescriptions unless the diagnosis was \u201cappropriate\u201d — which halted any off-label prescription requests.<\/p>\n The reason it\u2019s unclear is that Walz has been mum on why he rescinded his order. There\u2019s been no announcement or new stories. Local lawmakers told me they had no idea Walz had reversed course.<\/p>\n \u201cThere\u2019s been absolutely no transparency here,\u201d said Dr. Scott Jensen, a Republican state senator who criticized Walz\u2019s approach. Jensen, who has practiced medicine for more than 30 years in Minnesota, told me pharmacists he\u2019s worked with for years told him they could not fill a hydroxychloroquine prescription for COVID because of the March executive order.<\/p>\n He agrees that hydroxychloroquine is terribly misunderstood by the public and said politicians need to take a step back. \u201cHydroxychloroquine is one of the most studied drugs in the history of mankind,\u201d Jensen said. \u201cMy wife was on hydroxychloroquine for 15 years. It\u2019s been on the World Health Organization\u2019s list of essential medicines for decades. It\u2019s been in play since 1955, the year after I was born.\u201d<\/p>\n Hydroxychloroquine might be politically controversial, but that hasn\u2019t stopped some of its critics from taking advantage of the drug. In a May interview, former presidential hopeful Sen. Amy Klobuchar\u00a0admitted\u00a0<\/a>her husband was successfully treated with hydroxychloroquine, a medication she had\u00a0mocked\u00a0<\/a>on Twitter.<\/p>\n The politics of hydroxychloroquine are unlikely to cool before November\u2019s presidential election. \u00a0Yet, if Walz\u2019s decision is any indication, at least some leaders are starting to recognize the ethical dilemma of using the long arm of government to stand between suffering patients and a drug that may have the potential to save them.<\/p>\n